Preheat your oven to 350°F.
Combine the beef, bread, egg, onion, salt, pepper, 4 tbsp ketchup and milk in a bowl. Mix until all ingredients are evenly distributed. Place the meat into a baking dish, forming a rectangular form. Smooth the tops and sides.
In a separate bowl, combine the Worcestershire sauce and 1/2 cup ketchup. Spread evenly over the top and sides of the meatloaf.
Place pan into oven and cook for 1 hour to 1 hour 15 minutes, or until done.